The Comfort Hotel Hiroshima Otemachi is conveniently located in the business and leisure area, within walking distance of the Chuden-mae tram stop and minutes from the JR Hiroshima Station. This Hiroshima hotel is close to sightseeing spots like Hiroshima Peace Memorial Park and the Hiroshima Peace Memorial Museum, also called the Genbaku Dome, the Atomic Bomb Dome or the A-Bomb Dome.

In addition, Hiroshima City Hall, Naka Ward Office and Chugoku Electric Power Co.,Inc. are also nearby. Several shops and a variety of restaurants are within walking distance.